2025 NFC South Betting Odds

The NFC South has spent years carrying the label of one of the NFL’s weakest divisions, and while it hasn’t completely shed that reputation in 2025, the picture through…

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BestOddsBetting OddsNFLNFC South Betting
Published:Aug 27, 2025
Updated:Oct 18, 2025
Brent BooherSenior Writer
Brian Deschamps
Fact Checker
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The Buccaneers have jumped out as the clear front-runner in the division and the current front-runner to represent the NFC in the Super Bowl with a 5-1 record, thanks in large part to the incredible play of Baker Mayfield.

Mayfield has played at an MVP-caliber level and the Bucs have hummed on offense all season thanks to Baker essentially putting an injury-riddled offense on his shoulders. Emeka Egbuka was the front-runner to be named Rookie of the Year up until his recent hamstring injury in the Bucs win over the equally banged up 49ers in Week 6, while Mike Evans and Chris Godwin have each missed time recovering from injuries of their own. When all three of those guys are back on the field for Tampa, this is a very dangerous team in the NASCAR division of the NFC.

The Bucs lone threat in the South figures to be that of the Atlanta Falcons, who have performed as one would expect the Falcons to perform, great one week and completely lost the next. This is a team that dominated the Vikings and Bills but also lost 30-0 to the Panthers. They’re a bit hard to read but the talent is certainly there for them to make some noise in the NFC. Bijan Robinson is a legitimate candidate to win NFL Offensive Player of the Year and Michael Penix seems to be growing more comfortable each week.

Carolina has been an equally difficult team to read, as they have rattled off a pair of home wins against the Dolphins and Cowboys to get back to .500, which both of those defenses making Rico Dowdle look like peak LaDainian Tomlinson, when they have gone on the road they have looked very not good. The Panthers are 3-0 at home where they have scored just under 30 points per game. They are 0-3 on the road where they have only scored just a hair over 14 points per contest. They don’t look playoff caliber just yet, but teams visiting Charlotte may be in for a tough fight and the Panthers could certainly shake up some things in the playoff race.

Lastly, the Saints have shown some fight but just lack the talent on their roster to close out games. They’re 1-5 and not very likely to win too many games this season, which is something they actually may not be completely upset about with the rebuild that awaits them.

Before we jump head first into the NFC South, here’s a look at the odds to win the division entering Week 7.

USATSI 27309829 - Portrait of quarterback in action.

Odds to Win 2025 NFC South Entering Week 7

TeamCurrent Odds to
Win NFC South
Odds to Win
NFC South Entering Week 5
Odds to Win
NFC South Entering Week 3
Preseason Odds to Win NFC South
Tampa Bay Buccaneers-320-240-180-105
Atlanta Falcons+350+290+200+230
Carolina Panthers+1700+1300+1700+400
New Orleans Saints+6500+2700+2200+1300

The Bucs’ odds to win the South have strengthened to their season-high at -320, meaning you’d have to lay $320 to win $100 on the Bucs winning the division at this point in the season, a bet that may feel safe to make but does not hold any value whatsoever. 

The Falcons’ odds to win the South have slid to +350, but if you are looking to jump into the NFC South futures market at this point in the season, this is the best bet you can probably make at this point. Not to say I believe the Falcons will win the division, but they certainly have the talent to stick around should the Bucs begin to stumble.

The Panthers sit at 17-1 despite having a 3-3 record, but their struggles on the road are enough to rule them out of this race.

The Saints would need an act of God to win this division and +6500 is way too low to back this team.

USATSI 27318672 - Portrait with football player.

2025 NFC South Win Totals

As one would probably expect, the NFC South is not expected to light the NFL on fire this season, and so far it’s only the Bucs and Falcons who are making noise.  

If you ever need that confirmation as to what oddsmakers think of the division, look no further than the projected win totals for each of the four teams after the first month of play. 

TeamCurrent Win Totals and
Betting Odds
Win Totals and Betting Odds Entering Week 5Win Totals and Betting Odds Entering Week 3Preseason Win Totals and
Betting Odds
Tampa Bay BuccaneersO/U 11.5 | (-125/+105)O/U 10.5 | (+105/-125)O/U 10.5 | (-120/+100)O/U 9.5 | (+100/-120)
Atlanta FalconsO/U 9.5 | (-110/-110)O/U 8.5 | (+100/-120)O/U 9.5 | (+110/-130)O/U 7.5 | (-135/+115)
Carolina PanthersO/U 6.5 | (-120/+100)O/U 5.5 | (+105/-125)O/U 5.5 | (+120/-140)O/U 6.5 | (-130/+110)
New Orleans SaintsO/U 4.5 | (-105/-115)O/U 4.5 | (+115/-135)O/U 4.5 | (-110/-110)O/U 5.5 | (+140/-165)
  • The Bucs win total continues to climb as it now sits at 11.5 with juice on the over. If you took the Bucs at even money to win 9.5 games back before the season started you are feeling very good right about now. The Bucs are already half way to clearing the over six games into the season.

  • The Falcons win total number has returned to 9.5 with big wins over the Bills and Commanders after sliding down to 8.5 following their 30-0 blowout loss to Carolina. They remain as one of the biggest enigmas in the sport, which is just what the Falcons always seem to do. They have felt like a team that will flirt with .500 all season long and the win total still reflects that. 


  • The Panthers have shown they will play well on their home field but are still figuring out how to win games on the road. Their home schedule still features dates against the Bills, Rams, Bucs, and Seahawks, so they should probably try to figure out that road thing soon.


  • The Saints win total has remained at 4.5 for most of the season and I still like the under 4.5 now as much as I did after Week 1. -115 feels like a gift. 

USATSI 27308969 - Portrait of player in action.

2025 NFC South – To Win Super Bowl 60 Odds

Entering Week 7, only Tampa and Atlanta really figure to have a say in the playoffs, and it remains to be seen if the Falcons will play consistent enough to be one of those playoff teams.

The Bucs certainly look like a team capable of a deep playoff run and their Super Bowl odds reflect that, moving to their shortest odds of the season at 20-1.

The biggest question circulating the Bucs at this point is just how many injuries on offense can they survive to keep this thing going, however, they will be a very tough out in January if they continue to play this well.

Here’s how the rest of the Super Bowl odds stack up for the NFC South representatives.

NFC South Teams – Super Bowl LX Odds

TeamCurrent Odds
to Win Super Bowl LX
Odds to Win Super Bowl LX Entering Week 5Odds to Win Super Bowl LX Entering Week 3Preseason Odds to Win Super Bowl LX
Tampa Bay Buccaneers+2000+3000+2200+2700
Atlanta Falcons+4500+8000+5000+6500
Carolina Panthers+35000+40000+40000+15000
New Orleans Saints+40000+40000+40000+40000
USATSI 27308527 - Portrait with quarterback in action.

2025 NFC South – Player MVP Odds

The NFL MVP is essentially just a coronation of who was the best quarterback in the NFL that season, and if you’re looking for great NFL MVP bets, this is not the division for you.

With that being said, here’s a look at how each of the four starters in this division measure up in the race for MVP.

PlayerCurrent Odds
to Win
NFL MVP
Odds to Win
NFL MVP
Entering Week 5
Odds to Win
NFL MVP
Entering Week 3
Preseason
Odds to Win
NFL MVP
Baker Mayfield (Buccaneers)+350+2200+2000+2500
Michael Penix Jr. (Falcons)+20000+17500+7500+6000
Bryce Young (Panthers)+50000+40000+17500+10000
Spencer Rattler (Saints)+50000+50000+35000NR

The Baker Mayfield MVP campaign is real. Entering Week 5, I mentioned that he had great value at 22-1. After two massive wins over the Seahawks and 49ers, Baker now is in a dead heat to win MVP along with Patrick Mahomes and Josh Allen.

Given the very real voter fatigue with Mahomes and the fact Josh Allen just won the award, the media narrative behind Baker will only intensify as the weeks go on and the Bucs keep winning games. If Tampa can go into Detroit and beat the Lions on MNF, the MVP chants will be at a fever pitch.

The other three quarterbacks have next to no chance to win this award.

Step-By-Step To Bet On Divisional Winners

1. Go to your favorite sportsbook and log in.
2. Look for the NFL tab.
3. Click on the Division’s tab from the drop-down menu.
4. Choose the odds and team you will bet on.
5. Place your bet from the bet slip window—usually—on the right side of the screen.

Betting Odds For NFC Divisions

2025 NFC West Division Odds

2025 NFC North Division Odds

2025 NFC East Division Odds

About the Author: Brent Booher

Die-hard sports fan and overall lover of everything sports betting. Best bet ever placed was a $20 wager on Manchester United to win by the exact score of 3-1 in the 2019 Champions League at 80:1.

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